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Designing minimal genomes using whole-cell models

In the future, entire genomes tailored to specific functions and environments could be designed using computational tools. However, computational tools for genome design are currently scarce. Here we present algorithms that enable the use of design-simulate-test cycles for genome design, using genom...

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Detalles Bibliográficos
Autores principales: Rees-Garbutt, Joshua, Chalkley, Oliver, Landon, Sophie, Purcell, Oliver, Marucci, Lucia, Grierson, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012841/
https://www.ncbi.nlm.nih.gov/pubmed/32047145
http://dx.doi.org/10.1038/s41467-020-14545-0