Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition

HPV-negative head and neck squamous cell carcinomas (HNSCCs) develop in precancerous changes in the mucosal lining of the upper-aerodigestive tract. These precancerous cells contain cancer-associated genomic changes and cause primary tumors and local relapses. Therapeutic strategies to eradicate the...

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Detalles Bibliográficos
Autores principales: van Harten, Anne M., de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Ganzevles, Sonja H., Hunter, Keith D., Leemans, C. René, van Beusechem, Victor W., Wolthuis, Rob M. F., de Menezes, Renée X., Brakenhoff, Ruud H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012863/
https://www.ncbi.nlm.nih.gov/pubmed/32047167
http://dx.doi.org/10.1038/s41598-020-58509-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012863/
https://www.ncbi.nlm.nih.gov/pubmed/32047167
http://dx.doi.org/10.1038/s41598-020-58509-2

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