Cargando…

Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition

HPV-negative head and neck squamous cell carcinomas (HNSCCs) develop in precancerous changes in the mucosal lining of the upper-aerodigestive tract. These precancerous cells contain cancer-associated genomic changes and cause primary tumors and local relapses. Therapeutic strategies to eradicate the...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Harten, Anne M., de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Ganzevles, Sonja H., Hunter, Keith D., Leemans, C. René, van Beusechem, Victor W., Wolthuis, Rob M. F., de Menezes, Renée X., Brakenhoff, Ruud H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012863/ https://www.ncbi.nlm.nih.gov/pubmed/32047167 http://dx.doi.org/10.1038/s41598-020-58509-2

Ejemplares similares

Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck
por: de Boer, D. Vicky, et al.
Publicado: (2017)

Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death
por: van Harten, Anne M., et al.
Publicado: (2019)

WEE1 inhibition sensitizes osteosarcoma to radiotherapy
por: PosthumaDeBoer, Jantine, et al.
Publicado: (2011)

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function
por: de Lange, Job, et al.
Publicado: (2015)

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection
por: Bachas, Costa, et al.
Publicado: (2018)

Targeted Treatment of Head and Neck (Pre)Cancer: Preclinical Target Identification and Development of Novel Therapeutic Applications
por: van Harten, Anne M., et al.
Publicado: (2021)

NK Cell-Dependent Antibody-Mediated Immunotherapy Is Improved In Vitro and In Vivo When Combined with Agonists for Toll-like Receptor 2 in Head and Neck Cancer Models
por: Gruijs, Mandy, et al.
Publicado: (2021)

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma
por: Pai, Govind, et al.
Publicado: (2023)

'Wees alert op trauma, juist bij een verstandelijke beperking'
por: de Boer, Dieuwke
Publicado: (2021)

Resection Margins in Head and Neck Cancer Surgery: An Update of Residual Disease and Field Cancerization
por: Pierik, Annouk S., et al.
Publicado: (2021)

Expression deregulation of mir31 and CXCL12 in two types of oral precancers and cancer: importance in progression of precancer and cancer
por: Chattopadhyay, Esita, et al.
Publicado: (2016)

Pedicures, wees alert op ‘coronatenen’
por: van Putten, Margreet
Publicado: (2020)

Air raids and the 'Wee' Hospital.
por: Logan, C. J. H.
Publicado: (2003)

DNA-Bound Platinum Is the Major Determinant of Cisplatin Sensitivity in Head and Neck Squamous Carcinoma Cells
por: Martens-de Kemp, Sanne R., et al.
Publicado: (2013)

Analysis of small-sample clinical genomics studies using multi-parameter shrinkage: application to high-throughput RNA interference screening
por: van de Wiel, Mark A, et al.
Publicado: (2013)

Precáncer oral : diagnóstico y tratamiento de lesiones potencialmente malignas
por: Thomson, Peter James
Publicado: (2015)

Molecular progression to cervical precancer, epigenetic switch or sequential model?
por: Nedjai, Belinda, et al.
Publicado: (2018)

No Evidence for FANCF Gene Silencing in Head-and-Neck Squamous Cell Carcinomas
por: Ameziane, Najim, et al.
Publicado: (2009)

Classifying the precancers: A metadata approach
por: Berman, Jules J, et al.
Publicado: (2003)

At the Crossroads of Molecular Biology and Immunology: Molecular Pathways for Immunological Targeting of Head and Neck Squamous Cell Carcinoma
por: Wondergem, Niels E., et al.
Publicado: (2021)

Candidate biomarkers in the cervical vaginal fluid for the (self-)diagnosis of cervical precancer
por: Van Ostade, Xaveer, et al.
Publicado: (2017)

Genetic Classification of Oral and Oropharyngeal Carcinomas Identifies Subgroups with a Different Prognosis
por: Smeets, Serge J., et al.
Publicado: (2009)

Candida and calcofluor white: Study in precancer and cancer
por: Kumar, Rashmi Santosh, et al.
Publicado: (2009)

Diagnosis of oral precancer with optical coherence tomography
por: Lee, Cheng-Kuang, et al.
Publicado: (2012)

Cutaneous Cancer and Precancer: A Practical Monograph
Publicado: (1938)

Thermocoagulation versus cryotherapy for the treatment of cervical precancers
por: Duan, Lyufang, et al.
Publicado: (2020)

Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors
por: de Ruiter, Emma J., et al.
Publicado: (2020)

A review of the most promising biomarkers for early diagnosis and prognosis prediction of tongue squamous cell carcinoma
por: Hussein, Aisha A., et al.
Publicado: (2018)

A genome‐wide siRNA screen for regulators of tumor suppressor p53 activity in human non‐small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment
por: Siebring‐van Olst, Ellen, et al.
Publicado: (2017)

A mobile-phone based high-resolution microendoscope to image cervical precancer
por: Grant, Benjamin D., et al.
Publicado: (2019)

A comprehensive assessment protocol including patient reported outcomes, physical tests, and biological sampling in newly diagnosed patients with head and neck cancer: is it feasible?
por: van Nieuwenhuizen, Annette J., et al.
Publicado: (2014)

Potentially novel options for treatment of HPV-attributable head and neck cancer
por: Brakenhoff, Ruud H.
Publicado: (2013)

In Vitro CRISPR-Cas12a-Based Detection of Cancer-Associated TP53 Hotspot Mutations Beyond the crRNA Seed Region
por: Kohabir, Kavish A.V., et al.
Publicado: (2023)

Mammary carcinoma behavior is programmed in the precancer stem cell
por: Damonte, Patrizia, et al.
Publicado: (2008)

Status of salivary lipid peroxidation in oral cancer and precancer
por: Shetty, Shishir Ram, et al.
Publicado: (2014)

Multispectral light scattering endoscopic imaging of esophageal precancer
por: Qiu, Le, et al.
Publicado: (2018)

Concentration of FAD as a marker for cervical precancer detection
por: Meena, Bharat L., et al.
Publicado: (2019)

Prevalence of oral parameters in smokeless tobacco-associated precancer
por: Negi, Monika, et al.
Publicado: (2019)

Using Dynamic Features for Automatic Cervical Precancer Detection
por: Viñals, Roser, et al.
Publicado: (2021)

Utility of Keratins as Biomarkers for Human Oral Precancer and Cancer
por: Vaidya, Milind, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3qoro661vk0eruags4hfl50ddu