Non-secretory renin reduces oxidative stress and increases cardiomyoblast survival during glucose and oxygen deprivation

Although the renin-angiotensin system usually promotes oxidative stress and cell death, renin transcripts have been discovered, whose transcription product may be cardioprotective. These transcripts encode a non-secretory renin isoform that is localized in the cytosol and within mitochondria. Here w...

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Detalles Bibliográficos
Autores principales: Wanka, Heike, Lutze, Philipp, Staar, Doreen, Albers, Alexander, Bäumgen, Inga, Grunow, Bianka, Peters, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012910/
https://www.ncbi.nlm.nih.gov/pubmed/32047214
http://dx.doi.org/10.1038/s41598-020-59216-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012910/
https://www.ncbi.nlm.nih.gov/pubmed/32047214
http://dx.doi.org/10.1038/s41598-020-59216-8

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