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Non-secretory renin reduces oxidative stress and increases cardiomyoblast survival during glucose and oxygen deprivation
Although the renin-angiotensin system usually promotes oxidative stress and cell death, renin transcripts have been discovered, whose transcription product may be cardioprotective. These transcripts encode a non-secretory renin isoform that is localized in the cytosol and within mitochondria. Here w...
Autores principales: | Wanka, Heike, Lutze, Philipp, Staar, Doreen, Albers, Alexander, Bäumgen, Inga, Grunow, Bianka, Peters, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012910/ https://www.ncbi.nlm.nih.gov/pubmed/32047214 http://dx.doi.org/10.1038/s41598-020-59216-8 |
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