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Synthesis, Bioevaluation, Structure-Activity Relationship and Docking Studies of Natural Product Inspired (Z)-3-benzylideneisobenzofuran-1(3H)-ones as Highly Potent antioxidants and Antiplatelet agents

For the first time, a series of highly potent natural product inspired substituted (Z)-3-benzylideneisobenzofuran-1(3H)-ones 28a-t, embraced with electron-withdrawing groups (EWG) and electron-donating groups (EDG) at site I and site II, were prepared and assessed for their in vitro antioxidant acti...

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Detalles Bibliográficos
Autores principales: Shyamlal, Bharti Rajesh Kumar, Yadav, Lalit, Tiwari, Mohit K., Mathur, Manas, Prikhodko, Jaroslav I., Mashevskaya, Irina V., Yadav, Dharmendra K., Chaudhary, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012914/
https://www.ncbi.nlm.nih.gov/pubmed/32047204
http://dx.doi.org/10.1038/s41598-020-59218-6