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Immune protection is dependent on the gut microbiome in a lethal mouse gammaherpesviral infection

Immunopathogenesis in systemic viral infections can induce a septic state with leaky capillary syndrome, disseminated coagulopathy, and high mortality with limited treatment options. Murine gammaherpesvirus-68 (MHV-68) intraperitoneal infection is a gammaherpesvirus model for producing severe vascul...

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Detalles Bibliográficos
Autores principales: Yaron, Jordan R., Ambadapadi, Sriram, Zhang, Liqiang, Chavan, Ramani N., Tibbetts, Scott A., Keinan, Shahar, Varsani, Arvind, Maldonado, Juan, Kraberger, Simona, Tafoya, Amanda M., Bullard, Whitney L., Kilbourne, Jacquelyn, Stern-Harbutte, Alison, Krajmalnik-Brown, Rosa, Munk, Barbara H., Koppang, Erling O., Lim, Efrem S., Lucas, Alexandra R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012916/
https://www.ncbi.nlm.nih.gov/pubmed/32047224
http://dx.doi.org/10.1038/s41598-020-59269-9