Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties. Case Study: Superdisintegrants

The presence of different excipient types/brands in solid oral dosage forms may affect product performance and drug bioavailability. Understanding the biopharmaceutical implications of superdisintegrant variability (changes in material properties), variation (changes in excipient amount) and interch...

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Detalles Bibliográficos
Autores principales: Zarmpi, Panagiota, Flanagan, Talia, Meehan, Elizabeth, Mann, James, Fotaki, Nikoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012964/
https://www.ncbi.nlm.nih.gov/pubmed/32048079
http://dx.doi.org/10.1208/s12248-019-0406-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012964/
https://www.ncbi.nlm.nih.gov/pubmed/32048079
http://dx.doi.org/10.1208/s12248-019-0406-y

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