Cargando…
Biguanides in combination with olaparib limits tumorigenesis of drug‐resistant ovarian cancer cells through inhibition of Snail
Ovarian cancer is the most lethal gynecological malignancy. Currently, new chemotherapeutic strategies are required to improve patient outcome and survival. Biguanides, classic anti‐diabetic drugs, have gained importance for theiri antitumor potency demonstrated by various studies. Olaparib is a PAR...
Autores principales: | Wang, Qiong, López‐Ozuna, Vanessa M., Baloch, Tahira, Bithras, Joanne, Amin, Oreekha, Kessous, Roy, Kogan, Liron, Laskov, Ido, Yasmeen, Amber |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013055/ https://www.ncbi.nlm.nih.gov/pubmed/31863638 http://dx.doi.org/10.1002/cam4.2738 |
Ejemplares similares
-
Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors
por: Philip, Charles-André, et al.
Publicado: (2017) -
Sequential therapeutic targeting of ovarian Cancer harboring dysfunctional BRCA1
por: Baloch, Tahira, et al.
Publicado: (2019) -
Targeted sequencing of histologically defined serous endometrial cancer reflects prognosis and correlates with preoperative biopsy
por: Octeau, David, et al.
Publicado: (2019) -
Inhibition of Poly ADP-Ribose Glycohydrolase Sensitizes Ovarian Cancer Cells to Poly ADP-Ribose Polymerase Inhibitors and Platinum Agents
por: Matanes, Emad, et al.
Publicado: (2021) -
Suppression of Homologous Recombination by insulin-like growth factor-1 inhibition sensitizes cancer cells to PARP inhibitors
por: Amin, Oreekha, et al.
Publicado: (2015)