RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1

Mammalian target of rapamycin complex 1 (mTORC1) is evolutionally conserved and frequently activated in various tumors, including colorectal cancer (CRC). It has been reported that the ribosome assembly factor Urb1 acts downstream of mTORC1/raptor signaling and contributes to digestive organ develop...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Zhang, Wei‐Sheng, Wang, Zheng‐Xia, Wu, Zhi‐Wei, Du, Bin‐Bin, Li, Lai‐Yuan, Chen, Yi‐Feng, Yang, Xiong‐Fei, Hao, Xiang‐Yong, Guo, Tian‐Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013072/
https://www.ncbi.nlm.nih.gov/pubmed/31886628
http://dx.doi.org/10.1002/cam4.2810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013072/
https://www.ncbi.nlm.nih.gov/pubmed/31886628
http://dx.doi.org/10.1002/cam4.2810

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