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Macrophages/Microglia Represent the Major Source of Indolamine 2,3-Dioxygenase Expression in Melanoma Metastases of the Brain

The manifestation of brain metastases in patients with advanced melanoma is a common event that limits patient's survival and quality of life. The immunosuppressive properties of the brain parenchyma are very different compared to the rest of the body, making it plausible that the current succe...

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Detalles Bibliográficos
Autores principales: Herrera-Rios, Dayana, Mughal, Sadaf S., Teuber-Hanselmann, Sarah, Pierscianek, Daniela, Sucker, Antje, Jansen, Philipp, Schimming, Tobias, Klode, Joachim, Reifenberger, Julia, Felsberg, Jörg, Keyvani, Kathy, Brors, Benedikt, Sure, Ulrich, Reifenberger, Guido, Schadendorf, Dirk, Helfrich, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013086/
https://www.ncbi.nlm.nih.gov/pubmed/32117271
http://dx.doi.org/10.3389/fimmu.2020.00120