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Identification of Key Coagulation Activity Determining Elements in Canine Factor VIII

It is well known that canine factor VIII (cFVIII) has a higher specific activity than does human FVIII (hFVIII), and it has been previously demonstrated that cFVIII light chain is able to enhance hFVIII activity. The goal of this study was to first determine which amino acids in cFVIII light chain w...

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Detalles Bibliográficos
Autores principales: Firrman, Jenni, Wang, Qizhao, Wu, Wenman, Dong, Biao, Cao, Wenjing, Moore, Andrea Rossi, Roberts, Sean, Konkle, Barbara A., Miao, Carol, Liu, LinShu, Li, Dong, Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013134/
https://www.ncbi.nlm.nih.gov/pubmed/32071925
http://dx.doi.org/10.1016/j.omtm.2019.12.019