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Identification of Key Coagulation Activity Determining Elements in Canine Factor VIII
It is well known that canine factor VIII (cFVIII) has a higher specific activity than does human FVIII (hFVIII), and it has been previously demonstrated that cFVIII light chain is able to enhance hFVIII activity. The goal of this study was to first determine which amino acids in cFVIII light chain w...
Autores principales: | Firrman, Jenni, Wang, Qizhao, Wu, Wenman, Dong, Biao, Cao, Wenjing, Moore, Andrea Rossi, Roberts, Sean, Konkle, Barbara A., Miao, Carol, Liu, LinShu, Li, Dong, Xiao, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013134/ https://www.ncbi.nlm.nih.gov/pubmed/32071925 http://dx.doi.org/10.1016/j.omtm.2019.12.019 |
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