lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF(β-TRCP)-Mediated Degradation of NRF2 in Pancreatic Cancer

Drug resistance is the major obstacle of gemcitabine-based chemotherapy for the treatment of pancreatic ductal adenocarcinoma (PDAC). Many long non-coding RNAs (lncRNAs) are reported to play vital roles in cancer initiation and progression. Here, we report that lncRNA SLC7A11-AS1 is involved in gemc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qingzhu, Li, Kai, Huang, Xuemei, Zhao, Chen, Mei, Yu, Li, Xinyuan, Jiao, Lin, Yang, Huanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013141/
https://www.ncbi.nlm.nih.gov/pubmed/32036249
http://dx.doi.org/10.1016/j.omtn.2019.11.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013141/
https://www.ncbi.nlm.nih.gov/pubmed/32036249
http://dx.doi.org/10.1016/j.omtn.2019.11.035

Ejemplares similares