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An insulin-inducible transcription factor, SHARP-1, represses transcription of the SIRT1 longevity gene
The rat enhancer of split- and hairy-related protein (SHARP)-1 genes encode insulin-inducible transcriptional repressors. A longevity gene, sirtuin 1 (SIRT1) encodes protein deacetylase. These play an important role in regulating hepatic glucose metabolism. In this study, to evaluate a correlation w...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013158/ https://www.ncbi.nlm.nih.gov/pubmed/32072026 http://dx.doi.org/10.1016/j.bbrep.2020.100743 |