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Computational modeling of novel quinazoline derivatives as potent epidermal growth factor receptor inhibitors
QSAR modelling on Thirty (34) novel quinazoline derivatives (EGFR(WT) inhibitors) as non-small cell lung cancer (NSCLC) agents was performed to develop a model with good predictive power that can predict the activities of newly designed compounds that have not been synthesised. The EGFR(WT) inhibito...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013192/ https://www.ncbi.nlm.nih.gov/pubmed/32072038 http://dx.doi.org/10.1016/j.heliyon.2020.e03289 |