A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target

BACKGROUND AND AIMS: GAS6 signaling, through the TAM receptor tyrosine kinases AXL and MERTK, participates in chronic liver pathologies. Here, we addressed GAS6/TAM involvement in Non-Alcoholic SteatoHepatitis (NASH) development. METHODS: GAS6/TAM signaling was analyzed in cultured primary hepatocyt...

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Detalles Bibliográficos
Autores principales: Tutusaus, Anna, de Gregorio, Estefanía, Cucarull, Blanca, Cristóbal, Helena, Aresté, Cristina, Graupera, Isabel, Coll, Mar, Colell, Anna, Gausdal, Gro, Lorens, James B., García de Frutos, Pablo, Morales, Albert, Marí, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013198/
https://www.ncbi.nlm.nih.gov/pubmed/31689560
http://dx.doi.org/10.1016/j.jcmgh.2019.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013198/
https://www.ncbi.nlm.nih.gov/pubmed/31689560
http://dx.doi.org/10.1016/j.jcmgh.2019.10.010

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