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SFRP1 in Skin Tumor Initiation and Cancer Stem Cell Regulation with Potential Implications in Epithelial Cancers

Wnt signaling is involved in the regulation of cancer stem cells (CSCs); however, the molecular mechanism involved is still obscure. SFRP1, a Wnt inhibitor, is downregulated in various human cancers; however, its role in tumor initiation and CSC regulation remains unexplored. Here, we used a skin ca...

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Detalles Bibliográficos
Autores principales: Sunkara, Raghava R., Sarate, Rahul M., Setia, Priyanka, Shah, Sanket, Gupta, Sanjay, Chaturvedi, Pankaj, Gera, Poonam, Waghmare, Sanjeev K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013199/
https://www.ncbi.nlm.nih.gov/pubmed/31928951
http://dx.doi.org/10.1016/j.stemcr.2019.12.006