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Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells

Long-term culture of primary cells is characterized by functional and secretory changes, which ultimately result in replicative senescence. It is largely unclear how the metabolome of cells changes during replicative senescence and if such changes are consistent across different cell types. We have...

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Detalles Bibliográficos
Autores principales: Fernandez-Rebollo, Eduardo, Franzen, Julia, Goetzke, Roman, Hollmann, Jonathan, Ostrowska, Alina, Oliverio, Matteo, Sieben, Torsten, Rath, Björn, Kornfeld, Jan-Wilhelm, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013233/
https://www.ncbi.nlm.nih.gov/pubmed/31983656
http://dx.doi.org/10.1016/j.stemcr.2019.12.012