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Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells
Long-term culture of primary cells is characterized by functional and secretory changes, which ultimately result in replicative senescence. It is largely unclear how the metabolome of cells changes during replicative senescence and if such changes are consistent across different cell types. We have...
Autores principales: | Fernandez-Rebollo, Eduardo, Franzen, Julia, Goetzke, Roman, Hollmann, Jonathan, Ostrowska, Alina, Oliverio, Matteo, Sieben, Torsten, Rath, Björn, Kornfeld, Jan-Wilhelm, Wagner, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013233/ https://www.ncbi.nlm.nih.gov/pubmed/31983656 http://dx.doi.org/10.1016/j.stemcr.2019.12.012 |
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