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Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Alterations in Low-Grade Gliomas: Report of a Novel Gene Fusion Partner in a Pilocytic Astrocytoma and Review of the Literature

Pilocytic astrocytoma is a low-grade glial neoplasm of the central nervous system (CNS) that tends to occur in the pediatric population and less commonly presents in adults. Hereditary pilocytic astrocytoma is often associated with germline genetic alterations in the tumor suppressor NF1, the gene r...

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Detalles Bibliográficos
Autores principales: Pattwell, Siobhan S., Konnick, Eric Q., Liu, Yajuan J., Yoda, Rebecca A., Sekhar, Laligam N., Cimino, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013287/
https://www.ncbi.nlm.nih.gov/pubmed/32082673
http://dx.doi.org/10.1155/2020/5903863