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CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine

Inflammation is a major contributor to tubular epithelium injury in kidney disorders, and the involvement of blood platelets in driving inflammation is increasingly stressed. CD154, the ligand of CD40, is one of the mediators supporting platelet proinflammatory properties. Although hypoxia is an ess...

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Detalles Bibliográficos
Autores principales: Dewitte, Antoine, Villeneuve, Julien, Lepreux, Sébastien, Bouchecareilh, Marion, Gauthereau, Xavier, Rigothier, Claire, Combe, Christian, Ouattara, Alexandre, Ripoche, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013356/
https://www.ncbi.nlm.nih.gov/pubmed/32089648
http://dx.doi.org/10.1155/2020/6357046