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Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration

Chronic neuroinflammation contributes to the pathogenesis of Parkinson’s disease (PD). However, cellular and molecular mechanisms by which chronic neuroinflammation is formed and maintained remain elusive. This study aimed to explore detailed mechanisms by which anti-inflammatory cytokine interleuki...

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Detalles Bibliográficos
Autores principales: Gao, Yun, Tu, Dezhen, Yang, Ru, Chu, Chun-Hsien, Hong, Jau-Shyong, Gao, Hui-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013455/
https://www.ncbi.nlm.nih.gov/pubmed/31940754
http://dx.doi.org/10.3390/ijms21020465