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Regulation of CFTR Biogenesis by the Proteostatic Network and Pharmacological Modulators

Cystic fibrosis (CF) is the most common lethal inherited disease among Caucasians in North America and a significant portion of Europe. The disease arises from one of many mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator, or CFTR. The most common disease-associa...

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Detalles Bibliográficos
Autores principales: Estabrooks, Samuel, Brodsky, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013518/
https://www.ncbi.nlm.nih.gov/pubmed/31936842
http://dx.doi.org/10.3390/ijms21020452