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A Sub-Clone of RAW264.7-Cells Form Osteoclast-Like Cells Capable of Bone Resorption Faster than Parental RAW264.7 through Increased De Novo Expression and Nuclear Translocation of NFATc1

The murine macrophage cell line RAW264.7 is extensively used as a progenitor to study osteoclast (OC) differentiation. RAW264.7 is a heterogeneous cell line, containing sub-clones with different abilities to form OCs. The aim of this study was to identify characteristics within the heterogeneous RAW...

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Detalles Bibliográficos
Autores principales: Mira-Pascual, Laia, Tran, Anh N., Andersson, Göran, Näreoja, Tuomas, Lång, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013577/
https://www.ncbi.nlm.nih.gov/pubmed/31947698
http://dx.doi.org/10.3390/ijms21020538