SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner

The Warburg effect is an emerging hallmark of cancer, which has the tumor suppressor p53 as its major regulator. Herein, we unveiled that p53 activation by (S)-tryptophanol-derived oxazoloisoindolinone (SLMP53-1) mediated the reprograming of glucose metabolism in cancer cells and xenograft human tum...

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Detalles Bibliográficos
Autores principales: Ramos, Helena, Calheiros, Juliana, Almeida, Joana, Barcherini, Valentina, Santos, Sónia, Carvalho, Alexandra T. P., Santos, Maria M.M., Saraiva, Lucília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013701/
https://www.ncbi.nlm.nih.gov/pubmed/31963392
http://dx.doi.org/10.3390/ijms21020596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013701/
https://www.ncbi.nlm.nih.gov/pubmed/31963392
http://dx.doi.org/10.3390/ijms21020596

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