Topical MTII Therapy Suppresses Melanoma Through PTEN Upregulation and Cyclooxygenase II Inhibition

Melanotan II (MTII), a synthetic analogue of the alpha-melanocyte stimulating hormone (α-MSH), has been applied for skin tanning in humans. However, the carcinogenic consequence of topical MTII has been equivocal. This study aims to delineate the anti-neoplastic efficacy and mechanism of MTII using...

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Detalles Bibliográficos
Autores principales: Wu, Jian-Ching, Tsai, Han-En, Hsiao, Yi-Hsiang, Wu, Ji-Syuan, Wu, Chieh-Shan, Tai, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013727/
https://www.ncbi.nlm.nih.gov/pubmed/31968661
http://dx.doi.org/10.3390/ijms21020681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013727/
https://www.ncbi.nlm.nih.gov/pubmed/31968661
http://dx.doi.org/10.3390/ijms21020681

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