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Topical MTII Therapy Suppresses Melanoma Through PTEN Upregulation and Cyclooxygenase II Inhibition
Melanotan II (MTII), a synthetic analogue of the alpha-melanocyte stimulating hormone (α-MSH), has been applied for skin tanning in humans. However, the carcinogenic consequence of topical MTII has been equivocal. This study aims to delineate the anti-neoplastic efficacy and mechanism of MTII using...
Autores principales: | Wu, Jian-Ching, Tsai, Han-En, Hsiao, Yi-Hsiang, Wu, Ji-Syuan, Wu, Chieh-Shan, Tai, Ming-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013727/ https://www.ncbi.nlm.nih.gov/pubmed/31968661 http://dx.doi.org/10.3390/ijms21020681 |
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