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Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence

Cerebral edema and contusion expansion are major determinants of morbidity and mortality after TBI. Current treatment options are reactive, suboptimal and associated with significant side effects. First discovered in models of focal cerebral ischemia, there is increasing evidence that the sulfonylur...

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Detalles Bibliográficos
Autores principales: Jha, Ruchira M., Bell, Josh, Citerio, Giuseppe, Hemphill, J. Claude, Kimberly, W. Taylor, Narayan, Raj K., Sahuquillo, Juan, Sheth, Kevin N., Simard, J. Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013742/
https://www.ncbi.nlm.nih.gov/pubmed/31936452
http://dx.doi.org/10.3390/ijms21020409