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Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases

There is a strong anticipated future for human induced pluripotent stem cell-derived hepatocytes (hiPS-HEP), but so far, their use has been limited due to insufficient functionality. We investigated the potential of hiPS-HEP as an in vitro model for metabolic diseases by combining transcriptomics wi...

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Detalles Bibliográficos
Autores principales: Holmgren, Gustav, Ulfenborg, Benjamin, Asplund, Annika, Toet, Karin, Andersson, Christian X, Hammarstedt, Ann, Hanemaaijer, Roeland, Küppers-Munther, Barbara, Synnergren, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014160/
https://www.ncbi.nlm.nih.gov/pubmed/31940797
http://dx.doi.org/10.3390/ijms21020469