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Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases
There is a strong anticipated future for human induced pluripotent stem cell-derived hepatocytes (hiPS-HEP), but so far, their use has been limited due to insufficient functionality. We investigated the potential of hiPS-HEP as an in vitro model for metabolic diseases by combining transcriptomics wi...
Autores principales: | Holmgren, Gustav, Ulfenborg, Benjamin, Asplund, Annika, Toet, Karin, Andersson, Christian X, Hammarstedt, Ann, Hanemaaijer, Roeland, Küppers-Munther, Barbara, Synnergren, Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014160/ https://www.ncbi.nlm.nih.gov/pubmed/31940797 http://dx.doi.org/10.3390/ijms21020469 |
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