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Molecular Alterations in the Stomach of Tff1-Deficient Mice: Early Steps in Antral Carcinogenesis

TFF1 is a peptide of the gastric mucosa co-secreted with the mucin MUC5AC. It plays a key role in gastric mucosal protection and repair. Tff1-deficient (Tff1(KO)) mice obligatorily develop antropyloric adenoma and about 30% progress to carcinomas. Thus, these mice represent a model for gastric tumor...

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Detalles Bibliográficos
Autores principales: Znalesniak, Eva B., Salm, Franz, Hoffmann, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014203/
https://www.ncbi.nlm.nih.gov/pubmed/31963721
http://dx.doi.org/10.3390/ijms21020644