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Interleukin-1 Beta Neutralization Attenuates Traumatic Brain Injury-Induced Microglia Activation and Neuronal Changes in the Globus Pallidus

Traumatic brain injury (TBI) increases the risk of delayed neurodegenerative processes, including Parkinson’s disease (PD). Interleukin-1beta (IL-1β), a key pro-inflammatory cytokine, may promote secondary injury development after TBI. Conversely, neutralizing IL-1β was found to improve functional r...

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Detalles Bibliográficos
Autores principales: Ozen, Ilknur, Ruscher, Karsten, Nilsson, Robert, Flygt, Johanna, Clausen, Fredrik, Marklund, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014296/
https://www.ncbi.nlm.nih.gov/pubmed/31936248
http://dx.doi.org/10.3390/ijms21020387