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Airborne Particulate Matter (PM(10)) Inhibits Apoptosis through PI3K/AKT/FoxO3a Pathway in Lung Epithelial Cells: The Role of a Second Oxidant Stimulus

Outdoor particulate matter (PM(10)) exposure is carcinogenic to humans. The cellular mechanism by which PM(10) is associated specifically with lung cancer includes oxidative stress and damage to proteins, lipids, and DNA in the absence of apoptosis, suggesting that PM(10) induces cellular survival....

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Detalles Bibliográficos
Autores principales: García-Cuellar, Claudia M., Chirino, Yolanda I., Morales-Bárcenas, Rocío, Soto-Reyes, Ernesto, Quintana-Belmares, Raúl, Santibáñez-Andrade, Miguel, Sánchez-Pérez, Yesennia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014458/
https://www.ncbi.nlm.nih.gov/pubmed/31940823
http://dx.doi.org/10.3390/ijms21020473