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TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation

How repetitive elements, epigenetic modifications, and architectural proteins interact ensuring proper genome expression remains poorly understood. Here, we report regulatory mechanisms unveiling a central role of Alu elements (AEs) and RNA polymerase III transcription factor C (TFIIIC) in structura...

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Detalles Bibliográficos
Autores principales: Ferrari, Roberto, de Llobet Cucalon, Lara Isabel, Di Vona, Chiara, Le Dilly, François, Vidal, Enrique, Lioutas, Antonios, Oliete, Javier Quilez, Jochem, Laura, Cutts, Erin, Dieci, Giorgio, Vannini, Alessandro, Teichmann, Martin, de la Luna, Susana, Beato, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014570/
https://www.ncbi.nlm.nih.gov/pubmed/31759822
http://dx.doi.org/10.1016/j.molcel.2019.10.020