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Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

BACKGROUND: Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This susceptibility may in part be caused by changes to the epigenetic landscape which consequently affect gene expression and lead to changes in lipid metabolis...

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Detalles Bibliográficos
Autores principales: den Broeder, Marjo J., Ballangby, Jarle, Kamminga, Leonie M., Aleström, Peter, Legler, Juliette, Lindeman, Leif C., Kamstra, Jorke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014624/
https://www.ncbi.nlm.nih.gov/pubmed/32051014
http://dx.doi.org/10.1186/s13072-020-0329-y