Cargando…

Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

BACKGROUND: Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This susceptibility may in part be caused by changes to the epigenetic landscape which consequently affect gene expression and lead to changes in lipid metabolis...

Descripción completa

Detalles Bibliográficos
Autores principales:	den Broeder, Marjo J., Ballangby, Jarle, Kamminga, Leonie M., Aleström, Peter, Legler, Juliette, Lindeman, Leif C., Kamstra, Jorke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014624/ https://www.ncbi.nlm.nih.gov/pubmed/32051014 http://dx.doi.org/10.1186/s13072-020-0329-y

Ejemplares similares

Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish
por: Kamstra, Jorke H., et al.
Publicado: (2017)

Gamma radiation induces locus specific changes to histone modification enrichment in zebrafish and Atlantic salmon
por: Lindeman, Leif Christopher, et al.
Publicado: (2019)

Altered Adipogenesis in Zebrafish Larvae Following High Fat Diet and Chemical Exposure Is Visualised by Stimulated Raman Scattering Microscopy
por: den Broeder, Marjo J., et al.
Publicado: (2017)

Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish
por: Kamstra, Jorke H., et al.
Publicado: (2018)

Zebrafish as a Model to Study the Role of Peroxisome Proliferating-Activated Receptors in Adipogenesis and Obesity
por: Den Broeder, Marjo J., et al.
Publicado: (2015)

The impact of microplastics on female reproduction and early life
por: Yang, Jiayi, et al.
Publicado: (2023)

Epigenetic, transcriptional and phenotypic responses in two generations of Daphnia magna exposed to the DNA methylation inhibitor 5-azacytidine
por: Lindeman, Leif Christopher, et al.
Publicado: (2019)

Transcriptional and Epigenetic Mechanisms Underlying Enhanced in Vitro Adipocyte Differentiation by the Brominated Flame Retardant BDE-47
por: Kamstra, Jorke H., et al.
Publicado: (2014)

Altered non-coding RNA expression profile in F(1) progeny 1 year after parental irradiation is linked to adverse effects in zebrafish
por: Martín, Leonardo, et al.
Publicado: (2021)

Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation
por: Sun, Si, et al.
Publicado: (2018)

Methyltransferase-independent function of enhancer of zeste homologue 2 maintains tumorigenicity induced by human oncogenic papillomavirus and polyomavirus
por: Khattri, Michelle, et al.
Publicado: (2023)

Tiling Histone H3 Lysine 4 and 27 Methylation in Zebrafish Using High-Density Microarrays
por: Lindeman, Leif C., et al.
Publicado: (2010)

Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis
por: Lv, Yun-Cheng, et al.
Publicado: (2016)

The Arabidopsis homologs of trithorax (ATX1) and enhancer of zeste (CLF) establish ‘bivalent chromatin marks’ at the silent AGAMOUS locus
por: Saleh, Abdelaty, et al.
Publicado: (2007)

The Arabidopsis homologs of trithorax (ATX1) and enhancer of zeste (CLF) establish ‘bivalent chromatin marks’ at the silent AGAMOUS locus
por: Saleh, Abdelaty, et al.
Publicado: (2016)

Enhancer of zeste homolog 2 is involved in the proliferation of endometrial carcinoma
por: JIA, NAN, et al.
Publicado: (2014)

Histone methyltransferase enhancer of zeste 2 polycomb repressive complex 2 subunit exacerbates inflammation in depression rats by modulating microglia polarization
por: Huang, Xuezhu, et al.
Publicado: (2022)

Enhancer of zeste homolog 2 enhances the migration and chemotaxis of dental mesenchymal stem cells
por: Ma, Huarui, et al.
Publicado: (2019)

Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies
por: Nakagawa, Makoto, et al.
Publicado: (2018)

Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis
por: Le Goff, Emilie, et al.
Publicado: (2015)

Targeting enhancer of zeste homolog 2 protects against acute kidney injury
por: Zhou, X., et al.
Publicado: (2018)

Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis
por: Hou, Tsung-Yun, et al.
Publicado: (2017)

Clinicopathological Analysis of Expression of Enhancer of Zeste Homologue 2 in Canine Mammary Carcinoma
por: Ren, Xiaoli, et al.
Publicado: (2022)

Enhancer of Zeste Homolog 2 Induces Pulmonary Artery Smooth Muscle Cell Proliferation
por: Aljubran, Salman A., et al.
Publicado: (2012)

Enhancer of Zeste Homolog 2 as an Independent Prognostic Marker for Cancer: A Meta-Analysis
por: Chen, Shuling, et al.
Publicado: (2015)

Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
por: Lv, Yang-Fan, et al.
Publicado: (2015)

Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis
por: Zhang, Qi, et al.
Publicado: (2017)

Comprehensive Analysis of the Expression Characteristics of the Enhancer of the Zeste Homolog 2 Gene in Pan-Cancer
por: Kang, Yuanyuan, et al.
Publicado: (2021)

Expression of Enhancer of Zeste Homolog 2 (EZH2) Gene in Acute Myeloid Leukemia
por: Hamed, Nahla A. M., et al.
Publicado: (2023)

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications
por: Ciarapica, Roberta, et al.
Publicado: (2011)

Correction: Enhancer of Zeste Homolog 2 Induces Pulmonary Artery Smooth Muscle Cell Proliferation
por: Aljubran, Salman A., et al.
Publicado: (2012)

Enhancer of zeste plays an important role in photoperiodic modulation of locomotor rhythm in the cricket, Gryllus bimaculatus
por: Hamada, Yoshimasa, et al.
Publicado: (2016)

Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells
por: Dahlby, Tina, et al.
Publicado: (2020)

Effects of enhancer of zeste homolog 2 and mucin 1 expressions on treatment response in breast cancer
por: Yetişir, Abdullah Evren, et al.
Publicado: (2023)

Enhancer of zeste homolog 2 is a negative prognostic biomarker and correlated with immune infiltrates in meningioma
por: Zeng, Jing, et al.
Publicado: (2022)

Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells
por: Crespo, Diego, et al.
Publicado: (2021)

Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation
por: Dahl, Hildegunn, et al.
Publicado: (2023)

Goats without Prion Protein Display Enhanced Proinflammatory Pulmonary Signaling and Extracellular Matrix Remodeling upon Systemic Lipopolysaccharide Challenge
por: Salvesen, Øyvind, et al.
Publicado: (2017)

A Mixture of Persistent Organic Pollutants and Perfluorooctanesulfonic Acid Induces Similar Behavioural Responses, but Different Gene Expression Profiles in Zebrafish Larvae
por: Khezri, Abdolrahman, et al.
Publicado: (2017)

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
por: Wagener, Nina, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_dt2ddpa1md8sknudkia73iraae