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Accumulation of DNA methylation alterations in paediatric glioma stem cells following fractionated dose irradiation

BACKGROUND: Radiation is an important therapeutic tool. However, radiotherapy has the potential to promote co-evolution of genetic and epigenetic changes that can drive tumour heterogeneity, formation of radioresistant cells and tumour relapse. There is a clinical need for a better understanding of...

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Detalles Bibliográficos
Autores principales: Danielsson, Anna, Barreau, Kristell, Kling, Teresia, Tisell, Magnus, Carén, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014676/
https://www.ncbi.nlm.nih.gov/pubmed/32046773
http://dx.doi.org/10.1186/s13148-020-0817-8