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Accumulation of DNA methylation alterations in paediatric glioma stem cells following fractionated dose irradiation
BACKGROUND: Radiation is an important therapeutic tool. However, radiotherapy has the potential to promote co-evolution of genetic and epigenetic changes that can drive tumour heterogeneity, formation of radioresistant cells and tumour relapse. There is a clinical need for a better understanding of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014676/ https://www.ncbi.nlm.nih.gov/pubmed/32046773 http://dx.doi.org/10.1186/s13148-020-0817-8 |