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A practical view of fine-mapping and gene prioritization in the post-genome-wide association era
Over the past 15 years, genome-wide association studies (GWASs) have enabled the systematic identification of genetic loci associated with traits and diseases. However, due to resolution issues and methodological limitations, the true causal variants and genes associated with traits remain difficult...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014684/ https://www.ncbi.nlm.nih.gov/pubmed/31937202 http://dx.doi.org/10.1098/rsob.190221 |