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A practical view of fine-mapping and gene prioritization in the post-genome-wide association era

Over the past 15 years, genome-wide association studies (GWASs) have enabled the systematic identification of genetic loci associated with traits and diseases. However, due to resolution issues and methodological limitations, the true causal variants and genes associated with traits remain difficult...

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Detalles Bibliográficos
Autores principales: Broekema, R. V., Bakker, O. B., Jonkers, I. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014684/
https://www.ncbi.nlm.nih.gov/pubmed/31937202
http://dx.doi.org/10.1098/rsob.190221

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