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The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains

BACKGROUND: The rate of S68G mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase has increased and is closely related to the K65R mutation among CRF01_AE-infected patients who failed treatment. We aimed to explore the temporal association of S68G and K65R mutations and disc...

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Detalles Bibliográficos
Autores principales: Li, Shengjia, Ouyang, Jinming, Zhao, Bin, An, Minghui, Wang, Lin, Ding, Haibo, Zhang, Min, Han, Xiaoxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014709/
https://www.ncbi.nlm.nih.gov/pubmed/32046664
http://dx.doi.org/10.1186/s12879-020-4836-z