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The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains
BACKGROUND: The rate of S68G mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase has increased and is closely related to the K65R mutation among CRF01_AE-infected patients who failed treatment. We aimed to explore the temporal association of S68G and K65R mutations and disc...
Autores principales: | Li, Shengjia, Ouyang, Jinming, Zhao, Bin, An, Minghui, Wang, Lin, Ding, Haibo, Zhang, Min, Han, Xiaoxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014709/ https://www.ncbi.nlm.nih.gov/pubmed/32046664 http://dx.doi.org/10.1186/s12879-020-4836-z |
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