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Comparative transcriptomic analysis reveals the significant pleiotropic regulatory effects of LmbU on lincomycin biosynthesis
BACKGROUND: Lincomycin, produced by Streptomyces lincolnensis, is a lincosamide antibiotic and widely used for the treatment of the infective diseases caused by Gram-positive bacteria. The mechanisms of lincomycin biosynthesis have been deeply explored in recent years. However, the regulatory effect...
Hlavní autoři: | , , , , |
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Médium: | Online Článek Text |
Jazyk: | English |
Vydáno: |
BioMed Central
2020
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Témata: | |
On-line přístup: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014725/ https://www.ncbi.nlm.nih.gov/pubmed/32050973 http://dx.doi.org/10.1186/s12934-020-01298-0 |