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Preparation of the standard cell lines for reference mutations in cancer gene-panels by genome editing in HEK 293 T/17 cells

BACKGROUND: Next Generation Sequencer (NGS) is a powerful tool for a high-throughput sequencing of human genome. It is important to ensure reliability and sensitivity of the sequence data for a clinical use of the NGS. Various cancer-related gene panels such as Oncomine™ or NCC OncoPanel have been d...

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Detalles Bibliográficos
Autores principales: Suzuki, Takayoshi, Tsukumo, Yoshinori, Furihata, Chie, Naito, Mikihiko, Kohara, Arihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014756/
https://www.ncbi.nlm.nih.gov/pubmed/32071619
http://dx.doi.org/10.1186/s41021-020-0147-2