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Quantitatively relating brain endothelial cell–cell junction phenotype to global and local barrier properties under varied culture conditions via the Junction Analyzer Program

BACKGROUND: The endothelial cell–cell junctions of the blood–brain barrier (BBB) play a pivotal role in the barrier’s function. Altered cell–cell junctions can lead to barrier dysfunction and have been implicated in several diseases. Despite this, the driving forces regulating junctional protein pre...

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Detalles Bibliográficos
Autores principales: Gray, Kelsey M., Jung, Jae W., Inglut, Collin T., Huang, Huang-Chiao, Stroka, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014765/
https://www.ncbi.nlm.nih.gov/pubmed/32046757
http://dx.doi.org/10.1186/s12987-020-0177-y