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Separating the signal from the noise in metagenomic cell-free DNA sequencing

BACKGROUND: Cell-free DNA (cfDNA) in blood, urine, and other biofluids provides a unique window into human health. A proportion of cfDNA is derived from bacteria and viruses, creating opportunities for the diagnosis of infection via metagenomic sequencing. The total biomass of microbial-derived cfDN...

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Detalles Bibliográficos
Autores principales: Burnham, Philip, Gomez-Lopez, Nardhy, Heyang, Michael, Cheng, Alexandre Pellan, Lenz, Joan Sesing, Dadhania, Darshana M., Lee, John Richard, Suthanthiran, Manikkam, Romero, Roberto, De Vlaminck, Iwijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014780/
https://www.ncbi.nlm.nih.gov/pubmed/32046792
http://dx.doi.org/10.1186/s40168-020-0793-4