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Separating the signal from the noise in metagenomic cell-free DNA sequencing

BACKGROUND: Cell-free DNA (cfDNA) in blood, urine, and other biofluids provides a unique window into human health. A proportion of cfDNA is derived from bacteria and viruses, creating opportunities for the diagnosis of infection via metagenomic sequencing. The total biomass of microbial-derived cfDN...

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Detalles Bibliográficos
Autores principales:	Burnham, Philip, Gomez-Lopez, Nardhy, Heyang, Michael, Cheng, Alexandre Pellan, Lenz, Joan Sesing, Dadhania, Darshana M., Lee, John Richard, Suthanthiran, Manikkam, Romero, Roberto, De Vlaminck, Iwijn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014780/ https://www.ncbi.nlm.nih.gov/pubmed/32046792 http://dx.doi.org/10.1186/s40168-020-0793-4

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