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Asparaginyl-tRNA Synthetase, a Novel Component of Hippo Signaling, Binds to Salvador and Enhances Yorkie-Mediated Tumorigenesis

Aminoacyl-tRNA synthetases (ARSs), which are essential for protein translation, were recently shown to have non-translational functions in various pathological conditions including cancer. However, the molecular mechanism underlying the role of ARSs in cancer remains unknown. Here, we demonstrate th...

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Detalles Bibliográficos
Autores principales: Yeom, Eunbyul, Kwon, Dae-Woo, Lee, Jaemin, Kim, Seok-Ho, Lee, Ji-Hyeon, Min, Kyung-Jin, Lee, Kyu-Sun, Yu, Kweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014954/
https://www.ncbi.nlm.nih.gov/pubmed/32117966
http://dx.doi.org/10.3389/fcell.2020.00032