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ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer

The Serine–Glycine–One-Carbon (SGOC) pathway is pivotal in multiple anabolic processes. Expression levels of SGOC genes are deregulated under tumorigenic conditions, suggesting participation of oncogenes in deregulating the SGOC biosynthetic pathway. However, the underlying mechanism remains elusive...

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Detalles Bibliográficos
Autores principales: Li, Kai, Wu, Jian-lin, Qin, Baifu, Fan, Zongmin, Tang, Qin, Lu, Weisi, Zhang, Haipeng, Xing, Fan, Meng, Manqi, Zou, Shaomin, Wei, Wenxia, Chen, Honglei, Cai, Jian, Wang, Huaiming, Zhang, Hui, Cai, Jiayue, Fang, Ling, Bian, Xiqing, Chen, Chuangqi, Lan, Ping, Ghesquière, Bart, Fang, Lekun, Lee, Mong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015059/
https://www.ncbi.nlm.nih.gov/pubmed/31772275
http://dx.doi.org/10.1038/s41422-019-0257-1